MCB 4207 Lecture Notes - Lecture 2: Arabinogalactan, Tlr2, Lipopolysaccharide
Document Summary
Population is becoming more susceptible to pathogen infection. Only 4 companies dealing with antibiotic production. Nosocomial: hospital acquired infections; are becoming a problem. Postsurgical/wound infections: soldiers, for example, encounter these frequently. Normal human microbiota: bacteria produce certain enzymes that aid us in digesting/degrading food. Bacteria have no membrane bound organelles: example. ***the only way mitochondria might be mentioned is if bacteria has invaded cell with mitochondria. Gram negative bacteria: thin peptidoglycan layer, lps, endotoxin, o antigen: often used to distinguish between bacteria; made of different sugars, most outer part, porins (for transport) Acid-fast membrane: thin outer layer, seems similar to gram negative, but , has mycolic acid, has arabinogalactan. Biofilms: bacterial community, of different species, attached to surface, due to slime layer. Pilli: attachment, some for motility, conjugation (ex. sex pillus, antigenic. Pmf: proton motive force: proton related part, energy part.
