HSC 4555 Lecture Notes - Lecture 22: Tachypnea, Cyanosis, Leukotriene
Document Summary
Common symptoms associated with acute airway obstruction include wheezing, feelings of tightness in the chest, dyspnea, cough, and increased sputum production. Expiratory and inspiratory wheezing, tachycardia, tachypnea, use of accessory muscles of respiration, intercostal retractions, orthopnea, agitation, and cyanosis may be present depending on the severity. Common causes include exposure to allergens; in nonallergic types, exercise, stress, exposure to pulmonary irritants, and occupational allergens area common causes (pg. Allergic (extrinsic) asthma is mediated by ige, which is produced in response to specific antigens. The ige binds to mast cells and causes them to release inflammatory chemicals in response to antigen (pgs. Cystic fibrosis is an autosomal recessive disorder of the exocrine glands resulting in alterations in chloride and water transport across the apical surface of epithelial cells. Cystic fibrosis primarily affects the pancreas, intestinal tract, sweat glands and lungs and causes the mucus- producing glands of the gastrointestinal tract to enlarge, generating excessive secretions.