BIOL 178 Lecture Notes - Lecture 4: Seminiferous Tubule, Anterior Pituitary, Androstenedione
6 Mar 2020
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Testes: spermatogenesis + tonic endocrine function, leydig (interstitial) cells, they produce testosterone in the presence of luteinizing hormone (lh, secrete androgens (c19 steroids, controlled by lh from anterior pituitary, androgens, functions: Cognition: testosterone - act as a prohormone for dht (via 5alpha-reductase) and. Estrogen (via aromatase: androstenedione - weak androgen, dihydrotestosterone (dht) - strong androgen; can"t be aromatized to estrogen, sertoli cells. Inside seminiferous tubules; controlled by fsh, testosterone: secretes: Mullerian inhibiting hormone - inhibits development of female accessory sex organs in early development; secrete protein. Inhibin - inhibits fsh release from anterior pituitary; secrete protein: hypothalamic-pituitary-testicular axis. Ovaries: oogenesis (producing gametes) + cyclical endocrine function, estrogens (c18 steroids, synthesized from androgens, genital tract maintenance, 2 sex characteristics, water retention, ca ++ metabolism, cognition, sexual behavior, maternal behavior, types of estrogen: Estriol (e3: progesterone (c21 steroid, pregnancy maintenance in mammals, sexual behavior, maternal behavior. Inhibits fsh release from anterior pituitary: relaxin (peptide, relaxes pelvic ligaments during pregnancy (loosening)
