PUBHLTH 147 Lecture Notes - Lecture 4: Diabetes Mellitus Type 2, Tachycardia, Somnolence

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Caffeine withdrawal: headache, drowsiness, weakness, apathy, decreased motor behavior. Increased muscle tension: sometimes nausea, vomiting, flu-like symptoms. Severity and duration of withdrawal depends on typical daily use. Usually starts 12-24 hours after stopping use, peaks 20-48 hours after stopping use. Withdrawal reversal hypothesis (james, 1991: caffeine use is maintained to avoid or eliminate withdrawal symptoms. Long-term effects: moderate use does not appear to negatively impact health and well-being, caffeine may increase blood pressure during stressful times, may help preve(cid:374)t liver disease, parki(cid:374)so(cid:374)"s disease, alzhei(cid:373)er"s disease, Type 2 diabetes mellitus: may improve long-term memory and cognitive functioning (more research needed) High levels of caffeine may slow down or hinder conception. Caffeine passes through placenta, but fetus is unable to metabolize it. Uncertain whether caffeine may cause spontaneous abortion or impair fetal growth. Half-life of caffeine increased during pregnancy (stays in body longer) May lead to caffeine withdrawal in newborns (irritability and sometimes vomiting)

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