PUBHLTH 101 Lecture Notes - Lecture 10: Framingham Heart Study, Prospective Cohort Study, Cohort Study

• School: UC-Irvine
• Department: Public Health
• Course: PUBHLTH 101
• Professor: David Timberlake

Document Summary

Cohort group of individuals who share a common circumstance or significant life event: many kinds of cohorts (e. g. birth cohorts, employment cohorts) Incidence of disease is compared in the exposed vs. non-exposed: cohort studies have distinct advantages over other observational designs (discussed up to this point, 2 different study populations are used in cohort studies. A general population group defined by person, place, or time: example: professional (cid:894)nurses(cid:859) health tudy(cid:895) or other sele(cid:272)ted groups, example: defined by place/residence such as framingham heart study. Used when the study exposure is fairly common: example: high blood pressure. Comparison group is part of the general cohort, an internal comparison group. Typically used when the study exposure is uncommon/unique: exemplifies the utility of investigating rare exposures. Usually requires an external comparison group: similar as possible to the special exposure group except for study exposure, general population is frequently chosen as external comparison group for occupational cohort studies.