PSY 302 Lecture Notes - Lecture 3: Choline Acetyltransferase, Myasthenia Gravis, Substantia Nigra
1 Feb 2018
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A low therapeutic index is a safe drug to take. 2 routes of administration intravenous and oral sensitization refers to decrease of effect of drug after prolonged use false tolerance refers to increase of effect of drug after prolonged use false a drug that blocks metabotropic receptor antagonist. 2 routes of administration subcutaneous and topical administrations exitoxicity occurs when the margin of safety is low false start with coa (mitochondria made) Coa recycled back pons (rem sleep) basal forebrain (learning in cortex, long term memory) medial septum (brain rhythms, short term memory in hippocampus) In parasympathetic system: digestion, sex arousal, decrease in hr. Botulinum toxin blocks ach release (paralysis, death, wrinkles) Black widow spider venom promotes ach release (convulsion, death) Neostigmine (ache inhibitor, does not cross bbb, pns only) Tyrosine (high protein in food) turned into l-dopa by enzyme. Substantia nigra: projects to basal ganglia (movement): nigro-striatal. Projects to limbic cortex (reinforcement, desire, emotions): mesolimbic.
