BSC 310 Lecture Notes - Lecture 36: Integrase, Hepadnaviridae, Provirus
22 Mar 2016
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Document Summary
Viruses with (-) ssrna genomes need to have a (+) strand made to serve as mrna (cid:1) (cid:1) (cid:1) Rabies is bullet-shaped with an extensive and complex envelope. Virions contain several enzymes that are essential for infection and including an rna replicase. Their genome must first be transcribed by the replicase before being translated. Occurs in the cytoplasm and generates two classes of rnas: 1 for mrnas and the other for the genome template (cid:1) Assembly of rhabdociruses is complex, requiring 2 different coat proteins for the nucleocapsid and envelope (cid:1) The nucleocapsid assembles first around the viral genome and the envelope is acquired when the virion buds from the host cell, picking up viral glycoproteins that were inserted into the host cell"s membrane (cid:1) (cid:1) (cid:1) Only found in animals and has caused a number of pandemics, including one in 1918 that killed millions of people (cid:1)
