BSC 310 Lecture Notes - Lecture 93: Vaccinia, Polyomaviridae, Dna Replication

• School: University of Alabama
• Department: Biological Sciences
• Course: BSC 310
• Professor: Julie Olson

Document Summary

Uniquely replicating dna animal viruses: two groups of dsdna viruses show unusual replication strategies: pox viruses and adenoviruses. In pox viruses, all replication events, including dna replication occur in the cytoplasm instead of the nucleus: pox viruses are important historically and medically (smallpox, cowpox) and are among the largest of all known viruses. In these viruses, the sequence of their genome and mrna is the same: bacteriophage ms2 is an icosahedral virus that infects e. coli by attaching to the pilus. Its overlapping genome encodes 4 proteins: coat proteins, lysis protein, maturation protein, and 1 subunit of rna replicase (the other subunits come from the host cell) Influenza virus: only found in animals and has caused a number of pandemics, including one in 1918 that killed millions of people, enveloped virus with a segmented genome (multiple pieces of ssrna make up the genome)