PSYC 465 Lecture Notes - Lecture 3: Tyrosine, Hypertonia, Catatonia
Document Summary
Natural history of neurotransmitter substance: 1) synthesis. Neurotransmitter molecules are synthesized from precursors under the influence of enzymes: 2) storage. Neurotransmitters are storage within synaptic vesicles held in the terminal button: 3) release. Synaptic vesicles fuse with the synaptic membrane and release their neurotransmitter contents into the synapse: 4) receptor interaction. Neurotransmitters being received by the post-synaptic cell. Lock and key model - neurotransmitter molecule fits into the receptor and causes an effect: 5) inactivation (terminate) Neurotransmitters need to be inactivated after they do their job. Reuptake - used and unused neurotransmitters are taken back up into the presynaptic cell intact to be used again. Enzymatic degradation - some kind of enzyme breaks the neurotransmitter down into parts so they can no longer function. Drugs that effect neurotransmitters: agonists and antagonists. Facilitate, enhance, potentiate, mimic the effective neurotransmitter. Took the heart out of a frog and placed it into the appropriate solution in order to keep it beating.