VTPP 423 Lecture 26: Diuretics and Antihypertensives
16 May 2020
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Digoxin derived from foxglove plant inhibit naik atpase in 9 nat intracellularly cell membrane. T cardiac contractility dysfunction chronic systolic heart failure orsymptomatic relief only certain arrhythmias in direct stimulation of vagus nerve in atrial arrhythmias. Premature ventricular contraction 9 other arrhythmias digitalis effect. Av nodal block contraindicated in heart block 9 b blockers. Gi upset neurologic toxicity u lethargic disoriented delirious visual disturbances as. Xanthopsia objects appear yellow exacerbated by hypokalemia a renal. T 42 life insufficiency concave scooped st segment p caused by loop diuretics diarrhea digoxin toxicity is reversed by digoxin immune fab. 1antibody fragments anti arrhythmic drugs can do renal clearance. Pde inhibitor so 4camp breakdown arteriolar dilation hypotension decreased after load. Bump the grump in venous 9 arteriolar dilation diuresis. Tbmp tcgmp in smooth rn cells decreased after load a preload. Angiotensin i vasoconstriction i tgfr u efferentarteriole constriction acts at pct to t nu05 reab. 9aldosterone release from adrenalcortex n mineralocorticoid n t cnat.
