BIMS 320 Lecture Notes - Lecture 6: Antibiotics, Gonorrhea, Viral Vector

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In a ma tte r of hours a s ingle ce ll ca n ge ne ra te a colony of thous a nds of ide ntica l ce lls. S tudie s in the 1940s a nd 1950s de s cribe d thre e me cha nis ms of ge ne tra ns fe r a nd re combina tion be twe e n ba cte ria. 100 kb in le ngth; e ncode s a bout 40 ge ne s. Microbiologis ts now know tha t conjuga tion is controlle d by ge ne s ca rrie d on the f pla s mid. Forma tion of the hfr chromos ome occurs ra re ly. It is a ls o us e d in the la bora tory to introduce dna into microbia l ce lls , pla nt ce lls , a nd a nima l ce lls.

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