PHS 4601 Lecture Notes - Lecture 7: Antiseptic, Red Blood Cell, Chemotherapy
5 Dec 2017
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Prepared scrupulously by methods designed to ensure that they meet pharmacopeial requirements for sterility, pyrogens, particulate matter, and other contaminants, and, where appropriate, contain inhibitors of the growth of microorganisms. Pyrogens - fever inducing compound when introduced to the body, caused by bacteria present in preparation. Particulate matter - refers to solution dosage forms (in this situation) particle free. Suspensions contain many particles but this is why they are only given im. Solutions are not to contain any visible particles. 8. 1. 2 routes of administration and permissible dosage forms. Emulsion is dispersion of liquid into another liquid, which is immiscible. Colloidal system contains nanoparticles of less than 500 nm. Subcutaneous (sc) - under the skin: ~ 1 ml (up to. particles can be larger than id) solutions, suspensions, emulsions. Intramuscular (im) - directly into muscle: ~ 2 ml (largest volume) solutions, suspensions, emulsions can be major blood vessels in the area of injection, so try to avoid these places.
