MATH 221 Lecture Notes - Lecture 17: Cell Adhesion Molecule, Cell Adhesion, Cadherin
Document Summary
Morphogenesis: organization of cells in the body into functional structures. Chapter 4: cell to cell communication: direction/# of cell divisions, cell shape changes. Inducer will bind to receptor and will have a signal. Cells congregate near other similar cells with similar adhesion molecules to maximize bonding (adhesion) strength creating a thermodynamically stable (less energy costing) tissue/structure. The position of the sorted populations reflects their positions in embryo. Finding is interpreted in terms of selective affinity. Figure 4. 3 explained: presumptive epidermal cells and neural plate cells dissociation of cells spontaneous reaggregation. Segregation of cell types: more adhesive cells on neural cells, which is why moved interior. Experiment- aggregates of embryonic amphibian cells: figure 4. 4. Mixed epidermis and mesoderm production of embryoid: 2. Mixed mesoderm and endoderm they are similar in quantity, but the embryoid, the endoderm on outside, mesoderm on inside: endoderm covers mesoderm because functionality.
