MATH 221 Lecture 15: exam 1 developmental study guide
Document Summary
They bind to 3"utr of mrnas, inhibiting their translation: cytoplasmic localization: the place of rna expression is localized. It has the outer endosteal layer which functions in maintaining a long term quiescent state and these are actually inactive. They can use paracrine factors to send the signal. They are interesting bc signaling happens via connection of cyonomes on other cells: e-m, epithelial cells are connected via sheets and tubes while mesenchymal cells are unconnected from each other and operate independently. The mesenchymal cells initiates gene activity in epithelial cells. This can happen via paracrine factors, breaking any adhesions allowing for cell movement: pluripotent cells form all cell types of an embryo but the trophoblast. They can be found in icm and pgcs. Modularity means that a gene can have many enhancer elements and each can turn it on in a different set of cells.
