BIOL 203 Lecture Notes - Lecture 11: Walther Flemming, Sister Chromatids, Spindle Apparatus

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22 Sep 2016
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Walther flemming (1882: developed dyes to observe chromosomes during mitosis and cytokinesis, coined the terms mitosis and chromatin. Unicellular: division of one cell reproduces the entire organisms. Multicellular: development from a fertilized cell, growth, repair. Integral part of the cell cycle: mitosis. Produces identical daughter cells (same dna: meiosis. Does not have full set of chromosomes (gametes) Dna in a cell makes up the cells genome. Eukaryotic multiple dna molecules (around 2m long: eukaryotic species. Dna is condensed into chromosomes many chromosomes in the nucleus of cells. Somatic cells (non reproductive): 2 sets of chromosomes (46 total) Gametes (reproductive cells): consists of chromatin, 1 set of chromosomes (23 total) When cell is not dividing chromosomes are long thin bers. After dna replication: fiber densely coils into two sister, duplicated chromosomes are made of of sister chromatids. Joined together by cohesions: centromere: region where chromatids attach most closely. Attachment area is mediated by proteins: some bind to dna, some condense dna.

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