10:832:350 Lecture Notes - Lecture 2: Higher Consciousness, Interpersonal Relationship, Emotional And Behavioral Disorders

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Genetic factors account for about half of the likelihood that an individual will develop addiction. Environmental factors interact with the person"s biology and affect the extent to which genetic factors exert their influence. Resiliencies the individual acquires (through parenting or later life experiences) can affect the extent to which genetic predispositions lead to the behavioral and other manifestations of addiction. Culture also plays a role in how addiction becomes actualized in persons with biological vulnerabilities to the development of addiction. Currently, addictionologists are conducting linkage analysis on the human genome in hopes of finding candidate genes that can be directly attributed to addiction. As it stands, our best understanding comes from correlation studies of genetics and other factors such as the comorbid diagnosis of mental illness. Other factors that can contribute to the appearance of addiction, leading to its characteristic bio-psycho-socio-spiritual manifestations, include:

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