01:830:340 Lecture Notes - Lecture 5: Thought Disorder, Avolition, Solitude

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26 Jul 2016
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95% history of behavior, social, & psychiatric disturbances prior to the onset of psychosis. Developmental precursors- speech, motor development, movement abnormalities, unusual though content, suspicion, substance abuse. Prodromal stage: 85% experience this initial stage, 1-2 years before serious symptoms, less severe, yet unusual, ideas of reference- ex. Passage in a book written just for you. Delusions: disorder of thought content, grandeur, persecution, capgras & cotard"s syndromes, gross misrepresentations of reality. Hallucinations: sensory experience in absence of environmental stimuli or input. Disorganized symptoms: speech- word salad, behavior. Catatonic behavior: odd mannerisms, echolalia- imitate words, echopraxia- imitate posture. Viral infection theory- pregnant women exposed to flu virus in 1st or 2nd trimester. Parental age- men who father children in advanced age more schizophrenic children. Neurodevelopmental model of schizophrenia: impaired neural connections not apparent until 15-20 yr, strong genetic influence 80, increased cortisol in adolescence causes increased dopamine.

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