01:830:301 Lecture Notes - Lecture 22: Lingual Papilla, Insular Cortex, Taste Bud

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Taste buds: create neural signals conveyed to brain by taste nerves, embedded in structures: papillae (bumps on tongue, each taste bud contains taste receptor cells, info is sent to brain via cranial nerves. Microvilli- slender projections on the tips of some taste bud cells that extend into the taste pore: they"re extensions of the cell membrane, contain the sites that bind to taste substances. Tastant- any stimulus that can be tasted. Tastant can be divided into 2 large categories: some are made up of small, charged particles that taste salty or sour, other tastants are perceived via g protein-coupled receptors (gpcrs) similar to that in the olfactory system. 4 basic tastes: salty, sour, bitter, sweet, umami- savory (may be a special case) Salty: salt is made up of 2 charged particles: cation and anion, ability to perceive salt is not static, liking for saltiness is not static. Chloride-deficiency in childhood leads to increased preference for salty foods later.

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