01:694:301 Lecture Notes - Lecture 13: Oat, Reaction Rate Constant, Atp Hydrolysis
23 Apr 2020
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Part i : e n z y m e t. ee#eeet. Milder rxn rates it has to proceed on time scale of rxn conditions living systems. Greater specificity coenzymes very specific for substrate (many (cid:8869) enzyme. Capacity for glucose 10000 x for regulation needs to sense changing metabolic needs sugars look alike) less affinity for another sugar. * works in specific conditions ph an h functional grp ( need atp ) Isomerases -change chemical arrangements (go in both directions) Good enzyme will have high kat over km. Ka association constant units f- ka tighter binding. E t s t e s - e t p ka ke. 1st order - things and order - things ! Km not intrinsic properly (cid:8869) constant helps define fraction of an enzyme occupied by substrate. Yue. fm/fym?q degree of occupancy degree of occupancy steady state assumption. ; - formation of es complex m-" 5"
