01:119:116 Lecture Notes - Lecture 25: Collagen, Adrenal Medulla, Atrioventricular Node

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Lecture 25 - circulation: basics of circulatory systems, types of circulatory systems. Some animals do not have a circulatory system. Blood vessels (3 types: arteries - away from heart, capillaries, veins. Arteries arterioles capillaries venules veins. Encloses heart: comparison of vertebrate circulatory system. Fish - low metabolic rate, slow system. Two-chambered heart - 1 atrium, 1 ventricle. Heart gills body heart. Amphibian - low metabolic rate, slow system. Three-chambered heart - 2 atria, 1 ventricle. Double circulation - more vigorous blood flow. Four chambered heart - 2 atria, 2 ventricles. Cardiac output - blood pumped/min by left ventricle. Backflow into ventricles: initiation of heartbeat. Sa node (sinotrial) = pacemaker - initiates beat. Autorhythmic - generates ap"s by ca2+ channels. Autorhythmic cells b/w right atrium & right ventricle. Purkinje fibers - signal spreads throughout ventricle. Fig 42. 8: regulation of the heartbeat. Baroreceptors - in blood vessels & chambers. From lumen out (lumen is lining of a tube)

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