01:119:116 Lecture Notes - Lecture 12: Cyclic Adenosine Monophosphate, Adenylyl Cyclase, Salivary Gland
15 Mar 2017
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Endocrine system i: intercellular communication, introduction to hormones. Hor(cid:373)o(cid:374)e (cid:894)fro(cid:373) the greek word (cid:862)to excite(cid:863)(cid:895: chemical messengers, secreted in body fluids (mostly blood, travels through body bathing all cells. Target cell any cell that has a receptor for the hormone. Types of communication are classified into 5 paths: Pheromones how do they differ from hormones: target is outside of the body not inside. What/who are they communicating with: others usually of the same species. Functions: define territory, warning of predators, attraction of mates. Local regulators can be: fatty acids (ex: prostaglandins, gases (ex: nitric oxide, viagra, polypeptides (ex: cytokines, growth factor) Three major chemical classes of hormones: polypeptides (ex: insulin, steroids 4 carbon rings cholesterol (ex: cortisol, amines from a single amino acid (ex: epinephrine) Water soluble (polypeptides & most amines) binds with proteins on outside of cell) Lipid soluble (non-polar and steroids) enters cell and binds with internal proteins: water soluble hormones.
