01:119:115 Lecture Notes - Lecture 60: Cytosol, Intermembrane Space, Acetyl Group

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1. through outer membrane: diffuses small pores concentration gradient: across inner membrane: active transport carrier protein needs e, oxidation of pyruvate to acetyl coa. The citric acid cycle (cac): also called krebs cycle. Only 4 atp produced ( 2 in glycolysis +2 in cac) In form of high e e- in nadh & fadh2. We need their e used to synthesize more atp: electron transport chain (etc) , chemiosmosis. E- pass down chain of 4 carriers by redox reactions. Carriers grouped in 4 complexes: i, ii, ii, and iv. I, iii, & iv also pump h+ from matrix to intermembrane space. E- transfer etc causes proteins to pump h+ to the intermembrane space: create h+ gradient. Atp synthase= a molecular mill: enzyme in inner mb. H+ gradient: h+ diffuse through back to matrix: causes rotation. Glucose nadh or fadh2 electron transport chain proton- motive force atp: each nadh:

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