01:119:115 Lecture Notes - Lecture 6: Lipid Bilayer, Signal Transduction, Amphiphile
Document Summary
Membrane proteins: stay in membrane because of their polarity, hold the structure, determine many membrane functions, can move laterally- nxot flip. Integral: chains of amino acids where the hydrophilic is on the top, inside, and bottom which allows it to stay glued to hydrophobic structure, peripheral, polar or non polar, mostly polar, one side or the other side. Membrane proteins functions: transport (moving hydrogen ions, passive (open tube) Ions flow freely: active (apply energy to move, enzymes, biological catalysts that make stuff happen, signal transduction. Cell identification: a, b, o: fluid mosaic model. Membrane components can move laterally within one layer of the membrane: lipids, proteins, carbs. Temperature: cold, solid membrane, heat, fluidy membrane. Length of tails: long tails, more fluid, short tails, more compact. Amt. of cholesterol: holds membrane so it doesn"t fall apart. Read pg 127 evolution of differences in membrane fluidity. Cholesterol reduced membrane fluidity at moderate temperatures but at low temperatures hinders and solidication.