01:119:115 Lecture Notes - Lecture 6: Fluid Mosaic Model, Amphiphile, Hydrophile

• School: Rutgers University
• Department: Biological Science
• Course: 01:119:115
• Professor: Stern Cardinale

Document Summary

Hydrophobic interactions form bilayers: fluid mosaic model. Membrane is a fluid structure with a mosaic of various proteins. Experiment: cells fused after an hour -> proteins had mixed. Conclusion: at least some membrane proteins can move with in plane of (proteins can mix) Proteins in membrane -> form pattern (tiles in mosaic) Other move laterally in fluid at low temperatures -> hinders solidification. Membrane proteins: six major functions transport enzymatic activity signal transduction cell-cell recognition intercellular joining attachment to the cytoskeleton and extracellular matrix (ecm) Glycoproteins attached to protein glycolipids attached to lipid. Membrane regulates movement of molecules in/out the cell using: Hydrophilic molecules (ions and polar molecules): transport proteins. Allow passage of hydrophilic substances across the membrane. Ion channels facilitate the diffusion of ions: lipid bilayer permeability, transport proteins, channel proteins, carrier proteins. Do not dissolve in and do not cross membrane easily. Specific: passive (7. 3): no energy (atp, active (7. 4): needs energy (atp, simple diffusion, osmosis, facilitated diffusion.