NROSCI 1030 Lecture Notes - Lecture 1: Major Depressive Episode, Psychotic Depression, Adjustment Disorder
Document Summary
In indonesia, suicide is rare because it is culturally frowned upon. Characteristics: dysphoric mood, anhedonia decrease interest in things that were once pleasurable, decreased weight or increased appetite/weight gain. Insomnia or hypersomnia: psychomotor agitation (pacing, ringing hands) or psychomotor depression (sitting w/out moving) Biology: depression is quite primitive to what we know about schizophrenia, role in depression, amygdala expression of emotion and anxiety/stress, frontal cingulate (cognitive emotional area recognize emotions, medial pfc regulating emotions. In a normal, the cingulate and the amygdala are involved in coordinating emotions. I(cid:374) depressed, (cid:455)ou do(cid:374)"t ha(cid:448)e this (cid:272)orrelated a(cid:272)ti(cid:448)it(cid:455) people are feeling emotions but not understanding the source of it. In the medial pfc, there are a couple parts that play a role: pre-limbic and ifpfc: pre-limbic area 32 which is involved with suppressing emotions. Ifpfc projects to the amygdala in an excitatory fasion the amygdala then projects to the hippocampus and ventropallidum inhibits da neurons.
