BIOLOGY 1101 Lecture Notes - Lecture 7: Blood Donation, Organ Transplantation, Cell Membrane

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All nutrients and waste have to get in and out through the cell membrane. Also, need to be able to diffuse to the middle of the cell. Problem: surface area grows more slowly than volume. Eukaryotic cells can get bigger than prokaryotes, due to increased efficiency (organelles) Surface area to volume is an important concept in biology. Protein channels allow specific molecules to pass through a membrane. Facilitated diffusion: movement of molecules down their concentration gradient through a transport protein embedded in the membrane. Does not require energy for each ion transported, the channel is basically a pore in the membrane that can be open or closed to a certain ion. Active transport: movement of a molecule which requires energy (atp) Often, but not always, movement against the concentration gradient. There are proteins in the membrane other than protein channels (important in medicine!) Receptor proteins bind to specific molecules and send signals to the cell based on that binding.

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