BIOL 2301 Lecture Notes - Lecture 4: Y Chromosome, Red Color, Mendelian Inheritance

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indigooyster587

15 Aug 2018

School

Northeastern University

Department

Biology

Course

BIOL 2301

Professor

Christopher Richardson

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Document Summary

11: important concepts ( review ) i. ii. Locus : physical location at a gone on a chromosome. Homologous pairs of forms of alternative chromosomes often contain a givengene. D homologous chromosomes: alleles in different genes assort independently in gametes in meiosis. Measure of genetic distance blw genes and allows as to construct. 1 , genetic maps wl the positions of along chromosomes genes. Km) l% recombination frequency = a b. located on non homologous chromosomes is not linked for a part on genes effectively unlinked same chromosomes of. Linkage and recombination require keeping track of which alleles are linked. " recombination frequency increases wl increasing distance blw genes: two basic configurations. " random alignment in metaphase i of non - homologous chromosomes cause independent assortment ( is ( or coupling ) configuration , A or b or where the wild type on one chromosome & mutant. Blabatb ttlbb a for example , in the cross.

Related Questions

Question 1: Why are marker alleles useful to study even though they do not actually affect the traits being studied? Explain in your own words the logic underlying QTL mapping.

Multiplie choice: The genetic signature of recent positive selection on a locus is ...

a)	high frequency and low linkage disequilibrium

b)	low frequency and low linkage disequilibrium

c)	high frequency and high linkage disequilibrium

d)	low frequency and high linkage disequilibrium

QUESTION 3 Which statement(s) is(are) not true about GWAS? a.GWAS scan the entire genome for QTLs b. Like QTL mapping, GWAS useintrogression lines. c. GWAS are used to calculate the distance incM of two genes involved in the same disease. d. A and B e. B and Cf. A, B and C

QUESTION 4 GWAS take advantage of linkage disequilibrium sincefor some markers there is a higher frequency association betweenmarker and a particular QTL. True False

ivorygoose685

Which of these statements is incorrect?

Syntenic genes are located on the same chromosome.

Independent assortment results in recombinant chromosomes.

You can reliably predict the relative genetic distance fromgenesâ physical distance on a chromosome.

Linked genes are always syntenic.

What is the relative genetic distance between two linked genesif the recombination frequency is 0.49?

0.49 cM

4.9 cM

49 cM

490 cM

What statement best explains the distortion in Mendelian ratiosobserved by Bateson & Punnett in 1905? (Reminder: they found anoverrepresentation of F2 offspring showing both dominant orrecessive phenotypes, and an underrepresentation of offspringdisplaying one dominant and one recessive phenotype)

Human error: they should have been more careful about theirexperimental setup.

Gene linkage: Genes for flower color and pollen shape arephysically close on the same chromosome, leading to a breakdown inthe independent assortment of the alleles for these traits.

Chromosome crossover: Homologous recombination of twochromatids during meiosis caused the alleles to shuffle, resultingin a breakdown of the independent assortment of the alleles forthose genes.

Random variation: No two situations are alike. In finitepopulations, you are going to get some variation across a mean.

When determining the relative genetic distance between twogenes, why is dihybrid back-cross preferable over traditionaldihybrid cross?

9:3:3:1 phenotypic ratio is easier to work with than 1:1:1:1ratio.

Genotypes of the offspring can be determined based on theirphenotype.

If the genes are independently assorted, the dihybrid back-crosswould result in only 2 genotypes in the F1 generation.

B and C

Why do we map genes?

To understand how genes interact with each other

Comparative genomics analysis

To determine the genotype of an organism

All of the above

coralox210

BIOL 2301 Lecture Notes - Lecture 4: Y Chromosome, Red Color, Mendelian Inheritance

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