GN 301 Lecture Notes - Lecture 8: Fibroblast Growth Factor Receptor 3, Epistasis, Punnett Square

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21 Dec 2017
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If (cid:449)e k(cid:374)o(cid:449) so(cid:373)eo(cid:374)e"s phe(cid:374)otype, if asked (cid:449)hat per(cid:272)e(cid:374)tage they (cid:449)ill (cid:271)e heterozygous, you are only looking at the punnet square squares that show that phenotype (ex: 2/3 not 2/4) Law of random segregation: heterozygous people make two gamete types equally frequently, each gamete has equal chance of getting either allele (50%, ex: ff, both f and f have equal chance of being passed down. Law of probability: if two events are independent, probability of both occurring is the multiplication product of the individual proba(cid:271)ility it"s: ex: ff x ff gives 3/4 free ear : 1/4 attached. Tt x tt gives 3/4 taste: 1/4 non taster. So if you want taster and free it is 3/4 x 3/4 = 9/16: can do this with the genotypes as well. If fi(cid:374)di(cid:374)g ga(cid:373)etes : # gametes= 2^n (n= # of heterozygous loci)

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