MMG 301 Lecture Notes - Lecture 3: Chemical Substance, Periplasm, Phosphoenolpyruvic Acid

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Lecture 3: the structure and function of the cell membrane. Amphipathic: has both hydrophilic and hydrophobic components. Have ether bonds: bactria and eukaryotes have ester bonds, may be a diether or tetraether. Anchor proteins: energy production, transport, chemical sensory, motility. May be on one side of the bilayer, or span across it transports charged, and large particles can move around in the membrane. Essential nutrients have a low concentration in nature: they must be collected against the concentration gradient. Simple transport: proton motive force drives event. Group translocation: substance undergoes chemical modification, energy derived from phosphoenolpyruvate. Abc transport system: mostly occurs in bacteria with periplasm. Region between cytoplasmic membrane and the outer membrane. Antiport: chemical substance moves in while another moves out. Example: glucose uptake in e. coli: phosphate added to glucose. Energy comes from phosphoenolpyruvate: process similar for other sugars. Protein binds to nutrient: carries it to transporter.

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