MMG 301 Lecture Notes - Lecture 19: Trp Operon, Lac Operon, Regulon
4 Apr 2017
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Lecture 19: compare and contrast operon and regulon. Post-translational regulation: explain how regulatory protein dimmers bind to their dna binding sites. They often specifically bind to short dna sequences that are inverted repeats; each protein subunit binds to one of the inverted repeats, on both strands of the dna: understand which type of regulation acts the fastest. Transcription: understand why transcription regulation saves the cell the most resources. Doesn"t waste the energy to make proteins: know the function of activator and repressor proteins. Repressor protein binds to operon to prevent transcription; activator protein binds to an inducer to allow for transcription: compare and contrast transcription inhibition by enzyme inhibition and enzyme induction. induction) Example: trp operon (enzyme repression) and lac operon (enzyme: know where repressor and activator binding sites are in relationship to the promoter. Repressor binds after and activator binds before: describe how transcription activation works.
