BIOL 3040 Lecture Notes - Lecture 1: Quantitative Genetics, Haplotype, Allele Frequency
Document Summary
How can it lead to an extension of the range of variation in a continuous trait: a latent variation is where there is so much mendelian variation within populations that not all possible genotypes could be represented. If two individuals that are heterozygous for all of these traits were mated, how many allelic combinations are possible for their gametes: 4, 8, 16, 32. By knowing which loci are on particular chromosomes, we can better understand their interactions with one another. Interested in the abc loci: abc or abc are haplotypes (how the loci are found together, aa bb cc are genotypes, allele frequencies do not always give unique haplotypes frequencies. They can be different: can be affected by physical linkage- two or more loci on the same chromosome. Ranges from 0. 25 to 0 to -0. 25. Repulsion: -0. 25 d<0 haplotype indep. : the human mn and ss blood groups are determined by closely linked genes on chromosome 4.
