BIOL 1201 Lecture Notes - Lecture 5: Troponin, University Of Manchester, Resting Potential
20 Jan 2016
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Document Summary
Q: when epinephrine binds to cardiac muscle cells, it speeds their contraction. When it binds to muscle cells of the small intestine, it inhibits their contraction. Direct contact: one cell physically directing contact with another (cell junctions and cell recognition) Local: one cell signaling cells in the adjacent area: paracrine (cell secreting regulatory molecules affecting surrounding cells) and synaptic signals (neurotransmitter signal molecules released by one cell bind to receptors on post- synaptic side of junction) Distant: signaling at a distance: hormonal signals (endocrine system) (signal molecules produces are diffused into bloodstream and bind to target cells at some distance) Signal reception: most of the receptors are protein bound in the plasma membrane, some of the receptors are proteins located in the cytoplasm of the target cell (mostly steroids which are permeable to membrane) If proteins are involved, high level of specificity. Cell is not permeable, so the receptor has to be outside the cell.
