MARKET 1 Lecture Notes - Lecture 12: Spindle Apparatus, Cell Plate, Centrosome
Document Summary
Life continues, replaces dead cells: passes on genetic information, universal (unicellular and multicellular) 1 g1: gap/growth phase 1, aim to recover from mitosis and prepare for s, dna checking, and repair occurs, synthesis of rna and proteins, generation of new organelles. 3 g2: gap/growth phase 2, aim to prepare for mitosis, more dna checking occurs, rna and protein synthesis resumes, cell confirms number of chromosomes and organelles present, microtubule synthesis begins for spindle. 4 mitosis: aim cell division, divides sister chromatids, nucleus and cytoplasm (cytokinesis) Prophase: centrosome = microtubule organising centre made up of centrioles and microtubules, kinetochore proteins added to centromere as glue , chromosomes replicated in s condense, mitotic spindle assembles between centrosomes. Prometaphase: nuclear envelope breaks down, chromosomes are attached to spindle via kinetochores and undergo active movement, cohesion removed between the chromatids. Metaphase: chromosomes aligned at the equator, kinetochore microtubules attach chromatids to opposite poles.