BIOL 3410 Lecture Notes - Lecture 5: Secretion, Apposition, Triskelion

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Transport vesicles bud off from one compartment and fuse with another. As they do so, they carry material as cargo from the lumen and membrane of the donor compartment to the lumen and membrane of the target compartment, as shown. Figure 13-3 the intracellular compartments of the eukaryotic cell involved in the biosynthetic- secretory and endocytic pathways. Each compartment encloses a space, called a lumen, that is topologically equivalent to the outside of the cell, and all compartments shown communicate with one another and the outside of the cell by means of transport vesicles. In the biosynthetic-secretory pathway (red arrows) protein molecules are transported from the er to the plasma membrane or (via late endosomes) to lysosomes. In the endocytic pathway (green arrows) molecules are ingested in vesicles derived from the plasma membrane and delivered to early endosomes and then (via late endosomes) to lysosomes. All of these retrieval pathways are shown with blue arrows.

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