BIOL-K - Biology BIOL-K 101 Lecture Notes - Lecture 7: Epidermolysis Bullosa, Atp Hydrolysis, Electron Transport Chain
26 Oct 2016
School
Department
Professor
Document Summary
Chapter 7: fig 7. 3: describe the singer and nicholson fluid mosaic model of cell membrane structure. Integral proteins are the mosaic while the phospholipid tails = fluid-mosaic: fig 7. 7: describe how membrane proteins (integral and peripheral membrane proteins) associate with the lipid bilayer. Compare and contrast the relative mobility of lipids vs. proteins in a typical plasma membrane. Integral has two parts: hydrophobic and hydrophilic while the peripheral protein is on the integral (periplasmic) side. Lipids are free to travel on the membrane while proteins are often tethered to the membrane through the cytoskeleton on the extracellular side. The ecm is made of of glycoproteins such as integrins, collagen, proteoglycans and fibronectin. Integrins are receptor proteins in the plasma membrane that ecm proteins bind to. Collagen make the fibronectin(ecm) more elastic and stronger. Proteoglycan attach to a single long polysaccharide mole(cid:272)ule. P side is internal and e is external.
