RIU 330 Lecture Notes - Lecture 78: Nephron, Immunofluorescence, Dysuria
10 Nov 2020
School
Department
Course
Professor
Document Summary
Circulatory disturbances: hypertension, atherosclerosis, disseminated intravascular coagulation. Acute renal failure (rpgn): crescentic glomerulonephritis (gn) Nephritic syndrome: acute gn, systemic lupus erythematosus (sle) Nephrotic syndrome: lipoid nephrosis, membranous nephropathy, focal segmental glomerulosclerosis. Isolated hematuria/ proteinuria: berger"s (iga) disease, sle. Red blood cell (rbc) casts, dysmorphic/ fragmented. Calcium stones: calcium phosphate or calcium oxalate stones (75%) Wilms" tumor: only neoplasm found in children; all others occur in older adults. Originate from epithelial cells of kidney or urothelium (transitional cell lining of pelvis, ureter, urinary bladder, posterior urethra) Common 27,000 new cases; 11,000 cancer- related deaths per year in u. s. Found in 5% of chronic end-stage kidney disease patients. Occurs in older adults (> 50 years) Typical triad (hematuria, flank pain, palpable abdominal mass) found only in 10% Nonspecific symptoms common, often found accidentally ( internist"s tumor ) Paraneoplastic syndromes: hypercalcemia, erythrocytosis, or amyloidosis (20%) Composed of immature cells resembling renal blastema.
