BIOL 2300 Lecture Notes - Lecture 2: Quorum Sensing, Chromosome, Genomics

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Chapter 7/8: microbial genetics: functional unit: gene, study of transfer of genes: genetics, study of dna: genomics. Flow of genetic information: vertical gene transfer: reproduction. Rna to protein: translation: horizontal gene transfer: transfer of genes between cells of the same generation. Dna: deoxyribonucleic acid: polymer of nucleotides, bases: adenine, guanine, cytosine, thymine, sugar: deoxyribose, two component strands: 3 hydrogen bonds: bacterial dna: circular. Rna: ribonucleic acid: polymer of nucleotides, bases: adenine, guanine, cytosine, uracil, sugar: ribose, three different types: mrna, rrna, trna, rna is an intermediate step from transcription to translation of dna to a protein. Two strands in bacterial transcription: (-) strand: template for rna synthesis resulting rna molecule is complementary to this strand, (+) strand: complementary to the (-) strand. Nucleotide sequence of the rna molecule is the same. Stops when it reaches terminator sequence: translation: 3 nucleotides for 1 amino acid trna contain specific amino acids and anticodons.

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