MCB 3020C Lecture Notes - Lecture 7: Acetyl-Coa, Oxaloacetic Acid, Catabolism

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5 Jan 2020
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Two reaction series are linked to energy conservation in chemoorganotrophs: fermentation and respiration: fermentation: anaerobic catabolism in which organic compounds donate and accept electrons, respiration: aerobic and anaerobic catabolism in which a donor is oxidized with. O2 or another compound (anaerobic) as an electron acceptor. Glycolysis: a common pathway for catabolism of glucose that forms two atp: glucose can be fermented or respired, atp produced by substrate-level phosphorylation: energy-rich phosphate bond from organic compound is transferred to adp, making atp. Three stages: stage i: preparatory, form key intermediates, stage ii: redox, stage iii (fermentation): redox, two atps are produced. Some fermentations allow additional atp synthesis from substrate-level phosphorylation. Fermentation- respiration switch is based on energetic benefit. Pyruvate is fully oxidized to co2 through citric acid and glyocxylate cycles. Citric acid cycle (cac): pathway through which pyruvate is completely oxidized to co2; much greater atp yield than fermentation: 1. The cac begins when the 2-carbon compound acetyl-coa condenses with the.

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