HLTH 220 Lecture Notes - Lecture 16: Sunscreen, Endocrine Society, Epiphyseal Plate
6 Dec 2016
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Document Summary
Vitamin d was designated a nutrient of public health concern in the 2015-2020 dietary guidelines. D3 from animal, d2 from non-animals (ex: mushrooms) In response to low blood calcium levels kidney forms 1,25 (oh)2d to increase calcium absorption and release calcium form bone. Caution: data regarding extra-skeletal functions of vitamin d largely from epidemiologic and in vitro studies; more data from well-designed clinical trials needed. Based on 25()h)d concentrations in the blood. Institute of medicine: guidelines for adequate bone and overall health for average healthy. Endocrine society: guidelines based on bone and other health outcomes, believes most of population with chronic disease at risk for deficient. Vitamin d sequestered in adipose, not efficiently utilized. Clinical manifestations: rickets (children): poor bone mineralization, softening of growth plates at the ends of bones. Symptoms: poor growth, bone pain, muscle weakness, skeletal deformities(bowed legs, thickened wrists and ankles, breastbone projection: osteomalacia (adults): softening of bones due to poor bone mineralization.
