BIOL 336 Lecture 5: lecture 5 notes

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Second messenger systems: takes time to make camp. G-protein gated ion channels: g protein has to go bind to channel activate channel and channel protein opens up and allows ions to move through. Ligand gated: binding to receptor opens channel (1 step: which of the following is correct regarding the endocrine system, true: Products secreted into interstitial fluid: can be true for paracrine and endocrine. It can regulate physiological function in the long-term. Products are carried through the blood: false: Effects are localized to neighboring cells --- travelled to bloodstream to farther cells. Endocrine secretions are always protein hormones --- could be amines, steroids: on the picture of a cell, indicate a possible location for a receptor for the chemical messenger epinephrine. Cell surface receptor: catacholamine group - epinephrine, normally, the adrenal medulla expresses high amounts of the enzyme phenylethanolamine-n- methyltransferase (pnmt).

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