PSY 433 Lecture Notes - Lecture 24: Anxiolytic, Partial Agonist, Zolpidem
29 Jul 2020
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The discovery of receptores benzodiapine receptors has been a fundamental milestone in psychopharmacological research. These specific receptors a are linked to gaba receptors, type a, and when they bind to them bzds produce an ature of the chlorine channels making the neuron more resistant to excitation. The highest density of bzd receptors is found in amygdala, suggesting that this place is important in the action of anxiolytic drugs. Barbiturates instead seem to be directly attached fijan to the chlorinechannels themselves. There are drugs that antagonize the action of bzd, sticking to benzodiapine receptors and displacing the bzds that were previously;for this reason they are used in the treatment of. Bzd poisoning. receptores caso some substances whose chemical structure is not benzodiaceceric however also act on. Bzd receptors and have hypnotic effect, such as zolpidem and zoplicon. These lower dosagec-on-dos dosis substances show hypnotic effect, but not muscle relaxant, or anticonvulsant,with less tendency to produce dependence
