BIOSC-116 Lecture Notes - Lecture 31: Amantadine, Chemoprophylaxis, Lipid Bilayer
9 Dec 2020
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Granulomatous lung diseases - acute, subacute, or chronic. Berylliosis (not sure if important, but would be easy to test) A granuloma is a dense aggregate of histiocytes. If it"s an infection you should be able to stain bacteria. If it"s aspiration you should see food particles. Looks like sarcoidosis, the only difference is known exposure. Granulomas and inflammation surround bronchioles (bronchovascular bundle) Granulomas tend to be loose lymphocytosis: >40% lymphocytes in bronchoalveolar lavage. Try to figure out what is causing it/cry. General features of these viruses including structure, genome, and replication. Replication: penetrates into virus via phagocytosis, assembly occurs in the nucleus but begins in the cytoplasm. Structure: enveloped virus, mostly spherical or ovoid with prominent spikes. Has a host derived lipid bilayer (ha na), inner shell, and nucleocapsid (contains genome) Genome: s/s (-) rna divided into 8 segments 5 structural proteins 3 non-structural proteins. Replication: the only rna virus that replicates in the nucleus.
