BIOSC-116 Lecture Notes - Lecture 20: Organ Transplantation, Ciclosporin, Health Promotion

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Outline the way in which vaccinations prevent infection. Vaccinations the first infection stimulates an immune response including the production of memory b and t cells. This results in the second infection being not even realised due to the large amounts of memory cells ready in the immune response. Vaccinations work by making your immune system think you have had the first infection, therefore allowing for the development/production of specific memory b and t cells for the infection/pathogen. This means that future infections from the same disease won"t be felt by the host as the immune system can easily suppress the pathogen through memory cells. Live, attenuated vaccines: weakened pathogens so that they can no longer harm you. Subunit vaccines: made with purified antigens (often made in a recombinant bacteria) Outline the reasons for the suppression of the immune response in organ transplant patients. When an organ is transplanted it is recognised by the immune system in the body as non-self.

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