BIOL 031 Lecture Notes - Lecture 25: Facilitated Diffusion, Catecholamine, Hypothyroidism
17 Sep 2020
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Document Summary
Thyroid gland consists of 2 lobes of endocrine tissue joined in middle by narrow portion of gland. Produce two iodine-containing hormones derived from aa tyrosine. Influences synthesis and degradation of carbohydrate, fat, and protein. Increases heart rate and force of contraction. Plays crucial role in normal development of nervous system. Nonpolar: carried in blood, passes directly through cell membrane. T4 converted into t3 once inside the cell. Stimulates expression of that gene (protein production) Secondary to a deficiency of trh, tsh, or both inadequate dietary supply of iodine. Cretinism- congenital hypothyroidism (you are born with it), mother didn"t have enough tsh for development of the child (impaired) Surgical removal of a portion of the over-secreting thyroid. 4 small organs located on posterior surface of the thyroid. Increases breakdown of bone matrix and inhibits ca2+ secretion from the kidneys. Calcium is in the bones, resorption from the bone when you take the calcium out.
