GEN-3020 Lecture Notes - Lecture 16: Transfer Rna, Hydrogen Bond, Peptide
8 Nov 2016
School
Department
Course
Professor
Document Summary
The genetic code stores information as triplet nucleotides in dna, this information is transcribed into an mrna that is complementary to one dna strand. The final gene product of gene expression is a linear series of amino acids as prescribed by the genetic code. Translation is the biological polymerization of amino acids into polypeptide chains. It requires amino acids, mrna, ribosomes, and trna. trna, or transfer rna, adapt genetic information in the form of mrna codons into corresponding amino acids. They are very small in size and very stable. Contain post-transcriptionally modified bases: enhance hydrogen bonding efficiency during translation. trna anticodons complement mrna and trna carries corresponding amino acids. Ribosomes have an essential role in expression of genetic information. They consist of ribosomal proteins and ribosomal rna (rrna). Before translation can proceed, trna molecules must be chemically linked to their respective amino acids (charged) by aminoacyl trna synthetase. There are over 20 different synthetases, one for each amino acid.
