GEN-3000 Lecture Notes - Lecture 12: Histone Code, Operon, Repressor

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5 Nov 2018
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Inducible: production is on when an inducer is present. Repressible: production is off when a product is present. Activator: when it is bound in activates transcription. Repressible system: system is on but we want to turn it off. So going to have to activate the repressor which gets it to bind. Operon-single transcriptional unit, contains series of genes, a promoter, and an operator. Going to have a regulatory protein made in the genome (a active or repressor) Polycistron: has a bunch of genes put together. A system that is off in which the repressor is binding to prevent polymerase from binding. But want to get repressor off to turn it on -precursor interacts with repressor to inactive it. Negative tells us we are looking a repressor. Repressible: system is on but wants to turn it off. Tend to be making something -once we have enough of product, do not need to make more.

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