BIOL-1100 Lecture Notes - Lecture 13: Rna Polymerase Ii, Polyadenylation, Gene Expression
9 Mar 2017
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Genotype to phenotype: learning outcomes, explain how dna sequences is related to gene expression, gene: unit of heredity. Promoter sequences found on both strands of dna. Gene expression: transcription: learning outcomes, apply knowledge of cell structure to gene expression. Initiation outline: rnap ii binds to promoter region of protein-coding gene, rnap ii binding involves breaking h-bonds between and unwinding two. Dna strands: rnap )) is (cid:498)finicky(cid:499, transcription factors make the promoter more attractive to the rnap ii. )nitiation isn"t over until the transcript is at least (cid:883)(cid:882) bases long: rnap makes false starts, termination. In certain prokaryotes, a termination sequence forces rnap to release the. Introns removed, exons condensed: prokaryotes vs. eukaryotes, transcription factors and promoters are a bit different, but functionally similar, rnaps are different, location is different, post-transcriptional mods in eukaryotes, prokaryote translation can start before transcription termination. Gene expression: translation: learning outcomes, apply knowledge of cell structure to gene expression.
