CAS PS 544 Lecture Notes - Lecture 1: Combined Oral Contraceptive Pill, Thalidomide, Miscarriage

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Ps544: lecture 1: brain development (part 2: teratogens a. i. Teratogens: environmental agents that can cause developmental abnormalities or spontaneous abortion during prenatal development a. i. 1. Infections, some medications, birth control pills, chemicals, environmental pollutants a. i. 1. a. A lot increase risk of miscarriage early in pregnancy a. i. 2. c. A lot pfc, early birth during late pregnancy a. ii. Number of teratogens to which the fetus is exposed a. v. Genetic variations: maternal hazards to prenatal development (not teratogens) b. i. Fe leaching out of bones bc not enough fe ingestion and baby leaches it out of where it can get it b. ii. 2. Stress- diverts oxygen away from fetus, affects development of fetus"s biological stress systems b. iv. 1. No stress and tons of stress are bad b. iv. 1. a. If baby has no stress during pregnancy then baby gets to real world and cannot respond to stress b. iv. 2. Shapes biological stress system of fetus: biological programming b. v. paternal age may also be a developmental hazard! b. v. 1.

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