CGS NS 201 Lecture Notes - Lecture 3: Meiosis, Chromosome, Thomas Hunt Morgan
9 Aug 2018
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Document Summary
Mutation occurs in less than 1% of populations. Point mutations change in a single nucleotide. Transition purine-to-purine or pyrimidine to pyrimidine (a to g or t to c) Transversion purine to pyrimidine or vice versa. Nonsense point mutation creates a stop codon. Polymorphism occurs in more than 1% of population. Sickle cell anemia one nucleotide difference changes the sequences, this results in quaternary protein huge problem. This can also be correlated to mendel"s idea of. Since the proteins determined the trait that is expressed, the sickle cell is caused by a point mutation and shows that even small mutations can make a huge difference in the outcome turns into a polymorphism. Here, the snp changes the physical structure of the allelic inheritance from our parents, where single-celled autosomal recessive traits only occur in people will two mutant recessive alleles. especially in africa. If you have a normal genotype of aa, you are susceptible to malaria and therefore can die.
