CAS BI 105 Lecture Notes - Lecture 12: Mitosis, Acrosome, Morula

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It involves signaling, mitosis, differentiation, apoptosis, migration all coordinated among cells. We start with one stem cell, which divides into two cells, one of which has its transcription factor (asymmetric cell division). Nonetheless, the nucleolus in eggs and sperm is the same size. Fertilization gametes meet, generating 1 celled diploid organism called zygote. Acrosomal reaction acrosome is a packet lled with enzymes which can digest the coating of the egg, the jelly coat. The sperm releases its nucleolus into the egg. Fusion depolarization prevents another sperm from binding (block of polyspermy, making sure that not multiple sperms can enter the egg) Cortical reaction sperm binding to egg triggers the release of ca2+ which hardens the protective envelope of the egg (zona pellucida) and triggers egg activation. Cleavage cell division (the single cell goes through a round of mitosis to create a ball of cells).

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